Using Nitroglycerin Pills

This is general information. Always follow the instructions of your physician. If his/her instructions seem to differ with what you see here, another good source of dependable information would be your pharmacist or the company that manufactured the pills. Their contact information will be on the package.

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Nitroglycerin pills should not be removed from the original glass container and stored in another container.

Nitroglycerin pills should be stored in the original bottle and the bottle kept tightly closed.

If you want to protect your bottle of pills beyond the original bottle, we reccommend inserting the entire bottle into special containers that have been designed for that purpose.
Do not place other medication in the nitroglycerin pills bottle.

Nitroglycerin is an inherently unstable chemical. It is especially susceptible to loss of potency when exposed to heat, light or moisture. The bottle that your nitroglycerin pills came in complies with U.S. Pharmacopoeia guidance. Manufacturers of nitroglycerin sublingual pills use these types of bottles. That is why your pharmacist dispensed the product in its original container.

With proper use and storage of the product in accordance with the manufacturer’s recommendations printed on the label and in the Package Insert, customers can expect acceptable product potency following routine opening and closing of the container up to the expiration date as shown on the nitroglycerin pill bottle. nitroglycerin pills should be discarded if it was improperly stored, or if the expiration date on the package has been exceeded.

Keep the bottle loose and away from your body to protect the medication from body heat. nitroglycerin tablets bottles should not be kept in trouser or shirt pockets. Here are some possible ideas:

The product could be carried in a briefcase, pocketbook, tote bag, or overcoat. Some people wear a “fanny-pack” in order to keep the product with them at all times.

We have containers that are specially designed to hold the 25 pill bottles. These containers can be worn as a pendant, or can clip onto something, such as a belt loop or key chain. You can get one free by making a donation. Take a look at it.

Your pharmacist may carry these types of containers, but if they don’t, they generally have access to order them. Containers such as these are also available through this website. NEVER REMOVE THE nitroglycerin pills FROM THE ORIGINAL CONTAINER, UNLESS THE PILL IS BEING IMMEDIATELY USED. If you choose to use one of these described containers, always put the original nitroglycerin pill bottle, with the lid securely closed on the bottle, into the container. Never pour your nitroglycerin pills directly into one of these containers.

Q and A
Q My nitroglycerin pills aren’t working because I’m not getting a headache, or I’m not getting the tingling sensation under my tongue.
A Judging the ability of a sublingual tablet to relieve angina by the presence of a tingling or burning sensation after a pill has been dissolved under the tongue is not completely reliable since some patients may be unable to detect these effects. Newer stabilized sublingual pills are making such potency testing less useful, since the stabilized pills may be less likely to produce these detectable effects (ref.: USP DI 2002; 22nd Ed. “Drug Information for the Healthcare Professional”)

Q Why isn’t there cotton in the bottle, or a safety seal or plastic shrink wrap around the lid of my nitroglycerin pill bottle?

A There are several reasons why the bottles come without cotton, and no seal inside or outside the lid.

1. Nitroglycerin products are inherently unstable. They are especially susceptible to loss of potency when exposed to heat or light. Sealing a bottle or carton necessitates that heat be applied to the bottle or carton. This could affect the potency of the product.
2. Cotton, rayon, or any other material in the bottle could affect the stability of the nitroglycerin. This could affect the potency of the product.
3. Most importantly, unlike many other medications, nitroglycerin pills are used by patients who need to get to the product immediately. A person suffering an angina attack may not have time to remove a safety seal, or try to remove cotton from a very small opening, in order to get to the medicine.

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